Protein-losing enteropathy caused by spontaneous superior mesenteric artery dissection with thrombosis

Protein-losing enteropathy (PLE) is a rare clinical condition caused by continuous protein leakage into the digestive tract, resulting in hypoproteinemia, which can be complicated by edema, ascites, and malnutrition (1). It is observed in association with various disorders. However, its association with isolated spontaneous dis- section of the superior mesenteric artery with thrombo- sis (DSMAT) has not been reported before. We describe a patient who exhibited PLE due to DSMAT, and discuss the possible mechanisms and treatment of refractory hypoproteinemia in this condition.